Sodium butyrate inhibits high glucose-induced inflammation by controlling the acetylation of NF-κB p65 in human monocytes.
Ha-Rin MoonJung-Mi YunPublished in: Nutrition research and practice (2022)
These results suggest that NaB suppresses HG-induced inflammatory cytokine production through HAT/HDAC regulation in monocytes. NaB has the potential for preventing and treating diabetes and its related complications.
Keyphrases
- high glucose
- endothelial cells
- oxidative stress
- signaling pathway
- diabetic rats
- type diabetes
- dendritic cells
- cardiovascular disease
- advanced non small cell lung cancer
- peripheral blood
- lps induced
- immune response
- pi k akt
- metabolic syndrome
- insulin resistance
- nuclear factor
- risk assessment
- cell proliferation
- human health
- fluorescent probe
- toll like receptor