Insight into the hypercoagulable state of high-risk thrombotic APS patients: Contribution of aβ2GPI and aPS/PT antibodies.

Elena PontaraMaria Grazia CattiniChunyan ChengElisa BisonGentian DenasVittorio Pengo

Published in: Journal of thrombosis and haemostasis : JTH (2020)

Aβ2GPI antibodies show a mild anticoagulant and moderate procoagulant effect in thrombin generation and moderate aPC resistance. Conversely, aPS/PT antibodies show a strong anticoagulant effect and a strong aPCr.

Keyphrases

end stage renal disease
atrial fibrillation
venous thromboembolism
ejection fraction
newly diagnosed
chronic kidney disease
high intensity
prognostic factors
peritoneal dialysis