Super-Enhancer-Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes.

Jingping Yang Difei ZhangMasaru MotojimaTsutomu KumeQing HouYu PanAiping DuanMingchao ZhangSong JiangJinhua HouJingsong ShiZhaohui QinZhihong Liu

Published in: Journal of the American Society of Nephrology : JASN (2021)

FOXC1/2 maintain podocyte differentiation through transcriptional stabilization. The genome-wide chromatin resources support further investigation of TFs' regulatory roles in glomeruli transcription programs.

Keyphrases

transcription factor
genome wide
diabetic nephropathy
high glucose
dna methylation
dna binding
public health
genome wide identification
endothelial cells
copy number
gene expression
binding protein