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Fetal Membrane Organ-On-Chip: An Innovative Approach to Study Cellular Interactions.

Lauren RichardsonJuan GneccoTianbing DingKevin OsteenLisa M RogersDavid M AronoffRamkumar Menon
Published in: Reproductive sciences (Thousand Oaks, Calif.) (2019)
The controlled environment of an FM-OO-C allows for improved signal propagation between cells by minimizing noise and highlighting the small changes between treatments that cannot be seen in conventional transwell devices. Fetal membrane-organ-on-chip provides a better interaction between cell types that can be used to study fetal-maternal signaling during pregnancy in future studies.
Keyphrases
  • induced apoptosis
  • stem cells
  • circulating tumor cells
  • air pollution
  • pregnant women
  • cell proliferation
  • signaling pathway
  • cell death
  • physical activity
  • pregnancy outcomes