Fetal Membrane Organ-On-Chip: An Innovative Approach to Study Cellular Interactions.
Lauren RichardsonJuan GneccoTianbing DingKevin OsteenLisa M RogersDavid M AronoffRamkumar MenonPublished in: Reproductive sciences (Thousand Oaks, Calif.) (2019)
The controlled environment of an FM-OO-C allows for improved signal propagation between cells by minimizing noise and highlighting the small changes between treatments that cannot be seen in conventional transwell devices. Fetal membrane-organ-on-chip provides a better interaction between cell types that can be used to study fetal-maternal signaling during pregnancy in future studies.