Amustaline (S-303) treatment inactivates high levels of Chikungunya virus in red-blood-cell components.

M AubryA LaughhunnF Santa MariaM C LanteriAdonis StassinopoulosD Musso

Published in: Vox sanguinis (2018)

Chikungunya virus was previously shown to be inactivated by the PI technology using amotosalen and ultraviolet A light for the treatment of plasma and platelets. This new study demonstrates that S-303/GSH can inactivate high titres of CHIKV in RBCs.

Keyphrases

red blood cell
zika virus
aedes aegypti
replacement therapy
disease virus