Kinetics of Viral Shedding for Outbreak Surveillance of Emerging Infectious Diseases: Modeling Approach to SARS-CoV-2 Alpha and Omicron Infection.
Ting-Yu LinAmy Ming-Fang YenSam Li-Sheng ChenChen-Yang HsuChao-Chih LaiDih-Ling LuhYen-Po YehTony Hsiu-Hsi ChenPublished in: JMIR public health and surveillance (2024)
The study provides new insights into dynamic Ct transitions, with the notable finding that Ct-up transitions toward recovery outpaced Ct-down and symptom-surfacing transitions during the presymptomatic phase. The Ct-up against Ct-down transition varies with variants and vaccination status. The proposed Ct-enshrined compartment model is useful for the surveillance of emerging infectious diseases in the future to prevent community-acquired outbreaks.