Examining the Longitudinal Relationship Between Olfactory Dysfunction and Frailty in Community-Dwelling, older US Adults.

Esther WangKristen E WroblewskiMartha K McClintockLeah J WittJayant M Pinto

Published in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2024)

Older US adults with anosmia face higher odds of becoming frail over 5 years, especially those in the prefrail stage. Olfactory dysfunction may serve as a surrogate marker for early-stage neurodegenerative diseases, which are strong contributors to frailty.

Keyphrases

community dwelling
early stage
oxidative stress
squamous cell carcinoma
rectal cancer
middle aged