Sex and age differences in social and cognitive function in offspring exposed to late gestational hypoxia.

Steve MabryE Nicole WilsonJessica L BradshawJennifer J GardnerOluwadarasimi FadeyibiEdward VeraOluwatobiloba OsikoyaSpencer C CushenDimitrios KaramichosStyliani GoulopoulouRebecca L Cunningham

Published in: Biology of sex differences (2023)

Our results indicate that hypoxia-associated pregnancy complications during late gestation can increase the risk for behavioral and physiological outcomes in offspring, such as social dysfunction, repetitive behaviors, and cognitive impairment, that are dependent on sex and age.

Keyphrases

cognitive impairment
high fat diet
healthcare
mental health
endothelial cells
weight gain
pregnant women
pregnancy outcomes
preterm infants
high frequency
preterm birth
oxidative stress
type diabetes
metabolic syndrome
body mass index