Parental age and the risk of bipolar disorder in the offspring: A systematic review and meta-analysis.

Natália Polga Pedro Macul Ferreira de Barros Luis Carlos Farhat Karla Mathias de Almeida Michael H Bloch Beny Lafer

Published in: Acta psychiatrica Scandinavica (2022)

Advanced paternal and maternal age were both associated with an increased risk of BD in offspring. Further studies are needed to investigate the mechanisms behind this association.

Keyphrases

bipolar disorder
high fat diet
major depressive disorder
birth weight
adipose tissue
insulin resistance
metabolic syndrome
physical activity
weight gain