Tumour-infiltrating CD4-, CD8- and FOXP3-positive immune cells as predictive markers of mortality in BRCA1- and BRCA2-associated breast cancer.

Nanna Jørgensen Thomas Vauvert F HviidLise B NielsenIda M H SønderstrupJens Ole EriksenBent EjlertsenAnne-Marie GerdesTorben A KruseMads ThomassenMaj-Britt JensenAnne-Vibeke Lænkholm

Published in: British journal of cancer (2021)

The results support a prognostic role of specific T-cell subsets in BRCA-associated breast cancer and the promising potential of targeting the immune system in the treatment of these patients.

Keyphrases

breast cancer risk
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
regulatory t cells
prognostic factors
type diabetes
risk factors
risk assessment
patient reported outcomes
drug delivery
peripheral blood
immune response
patient reported