An improved genome assembly uncovers prolific tandem repeats in Atlantic cod.

Ole K TørresenBastiaan StarSissel JentoftWilliam B ReinarHarald GroveJason R MillerBrian P WalenzJames KnightJenny M EkholmPaul PelusoRolf B EdvardsenAve Tooming-KlunderudMorten SkageSigbjørn LienKjetill S JakobsenAlexander J Nederbragt

Published in: BMC genomics (2017)

The inclusion of PacBio reads combined with the use of multiple assembly programs drastically improved the Atlantic cod genome assembly by successfully resolving long TRs. The high frequency of heterozygous TRs within or in the vicinity of genes in the genome indicate a considerable standing genomic variation in Atlantic cod populations, which is likely of evolutionary importance.

Keyphrases

high frequency
genome wide
transcranial magnetic stimulation
dna methylation
copy number
public health
early onset
transcription factor
genetic diversity
genome wide identification