Profiling the Mutational Landscape in Known Driver Genes and Novel Genes in African American Non-Small Cell Lung Cancer Patients.
Christine M LuskDonovan WatzaGreg DysonDouglas CraigValerie RatliffAngela S WenzlaffFulvio LonardoAliccia Bollig-FischerGerold BeplerKristen PurringtonShirish GadgeelKendra L SchwartzPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
These findings suggest that broader mutation profiling including both known and novel driver genes in African Americans with NSCLC will identify additional mutations that may be useful in treatment decision-making.
Keyphrases
- african american
- genome wide
- end stage renal disease
- decision making
- single cell
- bioinformatics analysis
- small cell lung cancer
- genome wide identification
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- genome wide analysis
- gene expression
- dna methylation
- smoking cessation