Gold Nanoparticles Reduce Food Sensation in Caenorhabditis elegans via the Voltage-Gated Channel EGL-19.

Meimei WangZhenzhen ZhangNing SunBaolin YangJihao MoDaping WangMingqin SuJian HuMiaomiao WangLei Wang

Published in: International journal of nanomedicine (2023)

Our results demonstrate that Au NPs affect food sensation by reducing the calcium transit in ASEL neurons, which further leads to reduced pharynx pumping and feeding defects. The toxicology studies of Au NPs from worms have great potential to guide the usage of Au NPs in the medical field such as targeted drug delivery.

Keyphrases

reduced graphene oxide
gold nanoparticles
sensitive detection
drug delivery
human health
cancer therapy
oxide nanoparticles
healthcare
spinal cord
risk assessment
visible light
quantum dots
spinal cord injury
case control