NRBP1 promotes malignant phenotypes of glioblastoma by regulating PI3K/Akt activation.

Anli ZhangShichao PengSibai SunShan YeYe ZhaoQiang Wu

Published in: Cancer medicine (2024)

This study shows that NRBP1 promotes malignant phenotypes in GBM by activating PI3K/Akt pathway. Hence, it can function as both a predictive indicator and a new target for therapies in GBM treatment.

Keyphrases

pi k akt
signaling pathway
cell proliferation
cell cycle arrest
cell death
combination therapy