Genetic ancestry and prostate cancer susceptibility SNPs in Puerto Rican and African American men.

Margarita Irizarry RamirezRick A KittlesXuemei WangJeannette Salgado-MontillaGraciela M Nogueras-GonzálezRicardo Sánchez-OrtizLourdes GuerriosKeila RiveraEbony ShahIna ProkhorovaPamela RobersonPatricia TroncosoCurtis A Pettaway

Published in: The Prostate (2017)

The SNP rs7824364, a local marker of WAA in the 8q24 region was associated with PCa among both AA and PR men and with increased WAA among PR men. This novel relationship of PCA risk loci, WAA with PCa and its phenotype among PR men deserves further study.

Keyphrases

genome wide
prostate cancer
african american
middle aged
dna methylation
radical prostatectomy
copy number