Elucidating the role of genetically determined metabolites in Diabetic Retinopathy: insights from a mendelian randomization analysis.

Yao TanZuyun YanJiayang YinJiamin CaoBingyu XieFeng ZhangWenhua ZhangWei Xiong

Published in: Acta diabetologica (2024)

Our study identifies 4-androsten-3beta,17beta-diol disulfate 2, a metabolite of androgens, as a significant protective factor against diabetic retinopathy, suggesting androgens as potential therapeutic targets.

Keyphrases

diabetic retinopathy
optical coherence tomography
ms ms
genome wide
gene expression
human health
risk assessment