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Expanding donor pool by utilizing deceased donors with snake envenoming.

Hari Shankar MeshramVivek KuteHimanshu PatelSanshriti ChauhanSudeep Desai
Published in: Clinical transplantation (2020)
In India, the deceased kidney transplant program is still in its preliminary stage, and accepting deceased donors with snakebite is just a forward step to expand the donor pool. We report here the outcome of 8 successful renal transplantations from brain-dead donors who died from a neurotoxic snakebite. We accepted them as donors as they had no evidence of hemotoxic snakebite. 7 recipients did well. 1 died due to sepsis with a functioning graft. 1 required renal biopsy that showed acute tubular necrosis. 1 required re-exploration due to graft collection due to a surgical issue. Patient and graft survival in follow-up were similar to other matched deceased donors in our center. According to our experience, utilizing brain-dead donors who died from a neurotoxic snakebite is safe and may dramatically expand the donor pool especially in countries where death due to snakebite is high in numbers.
Keyphrases
  • kidney transplantation
  • acute kidney injury
  • liver failure
  • case report
  • resting state
  • blood brain barrier
  • hepatitis b virus
  • drug induced
  • cerebral ischemia