Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion.
K Arun PrashanthDeepti JainR ManikandanSuman KalyanVimalraj VelayuthamR SurendranPublished in: European journal of hybrid imaging (2023)
A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA levels started increasing and clinically a recurrence was suspected. A restaging FDG PET-CT showed no obvious malignant disease. Patient presented again within a month with complaints of urinary retention and haematuria. CEA levels were further elevated, and Ga-68 FAPI-04 (FAPI) PET-CT was performed. FAPI PET-CT revealed prostatic and seminal vesicle disease involvement. Additionally, an MRI of pelvis was done and fused with FAPI PET for confirmation of prostatic involvement.
Keyphrases
- pet ct
- benign prostatic hyperplasia
- positron emission tomography
- radical prostatectomy
- contrast enhanced
- case report
- magnetic resonance imaging
- single cell
- rectal cancer
- squamous cell carcinoma
- prostate cancer
- pulmonary embolism
- diffusion weighted imaging
- low grade
- cell therapy
- stem cells
- computed tomography
- mesenchymal stem cells
- pet imaging