Impact of Pruritus on Quality of Life and Current Treatment Patterns in Patients with Primary Biliary Cholangitis.
Marlyn J MayoElizabeth CareyHelen T SmithAndrea R MospanMegan McLaughlinApril ThompsonHeather L MorrisRobert SandefurW Ray KimChristopher Bowlusnull nullCynthia LevyPublished in: Digestive diseases and sciences (2022)
The prevalence of pruritus was high in this population, and those reporting clinically significant pruritus had a higher likelihood of having advanced disease and worse quality of life. However, this study found that pruritus in PBC is under-treated. This may be due in part to ineffectiveness of current treatments, poor tolerance, or the lack of FDA-approved medications for pruritus.