miR-378 associated with proliferation, migration and apoptosis properties in A549 cells and targeted NPNT in COPD.
Guo-Qing QianQi LiaoGuoxiang LiFengying YinPublished in: PeerJ (2022)
These findings suggest that miR-378 can regulate the proliferation, migration, and apoptosis of A549 cells and target NPNT. miR-378 increased in COPD lung tissues while NPNT decreased, and might prove a potential target for novel drug therapy.
Keyphrases
- cell cycle arrest
- induced apoptosis
- cell proliferation
- long non coding rna
- cell death
- endoplasmic reticulum stress
- pi k akt
- signaling pathway
- long noncoding rna
- chronic obstructive pulmonary disease
- oxidative stress
- lung function
- emergency department
- stem cells
- cancer therapy
- cell therapy
- cystic fibrosis
- human health
- adverse drug