Guillain-Barré syndrome and COVID-19: an observational multicentre study from two Italian hotspot regions.
Massimiliano MirabellaStefano Cotti PiccinelliStefano GazzinaCamillo ForestiBarbara FrigeniMaria Cristina ServalliMaria SessaGiuseppe CosentinoEnrico MarchioniSabrina RavagliaChiara BrianiFrancesca CastellaniGabriella ZaraFrancesca BianchiUbaldo Del CarroRaffaella FazioMassimo FilippiEugenio MagniGiuseppe NataliniFrancesco PalmeriniAnna Maria PerottiAndrea BellomoMaurizio OsioGiuseppe ScopellitiMarinella CarpoAndrea RaseraGiovanna SquintaniPietro Emiliano DonedduValeria BertasiMaria Sofia CotelliLaura BertolasiGian Maria FabriziFederico RanieriFrancesca CaprioliElena GrappaLaura BroglioGiovanni De MariaUgo LeggioLoris PoliFrank RasuloNicola LatronicoEduardo Nobile-OrazioAlessandro PadovaniAntonino UnciniPublished in: Journal of neurology, neurosurgery, and psychiatry (2020)
This study shows an increased incidence of GBS during the COVID-19 outbreak in northern Italy, supporting a pathogenic link. COVID-19-associated GBS is predominantly demyelinating and seems to be more severe than non-COVID-19 GBS, although it is likely that in some patients the systemic impairment due to COVID-19 might have contributed to the severity of the whole clinical picture.