No association between DNA methylation and COPD in never and current smokers.

Maaike M De VriesDiana A van der PlaatJudith M VonkH Marike Boezen

Published in: BMJ open respiratory research (2018)

In contrast to a previous, smaller study, we did not observe any significant association between DNA methylation levels and the presence of COPD, independent of smoking status. Apparently, DNA methylation studies are highly variable.

Keyphrases

dna methylation
genome wide
chronic obstructive pulmonary disease
gene expression
smoking cessation
lung function
magnetic resonance
copy number
magnetic resonance imaging
cystic fibrosis
contrast enhanced