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Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles.

Eleonora ColomboDavide Andrea CoppiniSimone MaculanPierfausto SeneciBenedetta SantiniFilippo TestaLucia SalvioniGiovanni Maria VanacoreMiriam ColomboDaniele Passarella
Published in: RSC advances (2022)
Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.
Keyphrases
  • cancer therapy
  • drug delivery
  • walled carbon nanotubes
  • transition metal