Facile chemical routes to mesoporous silver substrates for SERS analysis.
Elina A TastekovaAlexander Yu PolyakovAnastasia E GoldtAlexander V SidorovAlexandra A OshmyanskayaIrina V SukhorukovaDmitry V ShtanskyWolgang GrünertAnastasija V GrigorievaPublished in: Beilstein journal of nanotechnology (2018)
Mesoporous silver nanoparticles were easily synthesized through the bulk reduction of crystalline silver(I) oxide and used for the preparation of highly porous surface-enhanced Raman scattering (SERS)-active substrates. An analogous procedure was successfully performed for the production of mesoporous silver films by chemical reduction of oxidized silver films. The sponge-like silver blocks with high surface area and the in-situ-prepared mesoporous silver films are efficient as both analyte adsorbents and Raman signal enhancement mediators. The efficiency of silver reduction was characterized by X-ray diffraction and X-ray photoelectron spectroscopy. The developed substrates were applied for SERS detection of rhodamine 6G (enhancement factor of about 1-5 × 105) and an anti-ischemic mildronate drug (meldonium; enhancement factor of ≈102) that is known for its ability to increase the endurance performance of athletes.
Keyphrases
- silver nanoparticles
- gold nanoparticles
- reduced graphene oxide
- room temperature
- high resolution
- highly efficient
- metal organic framework
- sensitive detection
- label free
- raman spectroscopy
- skeletal muscle
- emergency department
- minimally invasive
- quantum dots
- oxidative stress
- single molecule
- dual energy
- mass spectrometry
- brain injury
- crystal structure
- molecularly imprinted
- drug induced
- low density lipoprotein