Discordance between TST and QFT-TBGold Plus for Latent Tuberculosis Screening among Under-Five Children: An Interim Analysis.

Suchitra SurveVikrant BhorKajal NaukariyaShahina BegumKiran MunnePranita TipreNarendra SutarAkanksha JaiswalGauri BhondeSanjay ChauhanIra Shah

Published in: Journal of tropical pediatrics (2022)

The study strongly recommends both TST and QFT-TB Gold Plus test for the diagnosis of LTBI in under-five children. A moderate concordance in children <24 months endorses the reliability of QFT-TB Gold Plus in diagnosing LTBI in this age group. This study highlights the need for screening undernourished children for LTBI to consider repeating IGRA testing for TST positives as per the window period and risk of ongoing exposure.

Keyphrases

young adults
mycobacterium tuberculosis
emergency department
hiv aids
pulmonary tuberculosis
human immunodeficiency virus
hiv infected
electronic health record
adverse drug
antiretroviral therapy