Transition-Metal-Free Lactonization of sp2 C-H Bonds with CO2.
Zhen ZhangTao JuMeng MiaoJie-Lian HanYi-Han ZhangXing-Yong ZhuJian-Heng YeDa-Gang YuYong-Gang ZhiPublished in: Organic letters (2017)
The transition-metal-free lactonization of heteroaryl and alkenyl C-H bonds with carbon dioxide is reported to synthesize important coumarin derivatives in moderate to excellent yields. These redox-neutral reactions feature a broad substrate scope, good functional group tolerance, facile scalability, and easy product derivatization.
Keyphrases
- transition metal
- carbon dioxide
- ms ms
- machine learning
- high performance liquid chromatography
- liquid chromatography tandem mass spectrometry
- gas chromatography mass spectrometry
- high intensity
- deep learning
- fluorescent probe
- simultaneous determination
- quantum dots
- reduced graphene oxide
- highly efficient
- tandem mass spectrometry
- solid phase extraction
- mass spectrometry
- visible light