Network Analysis Reveals Protein Modules Associated with Childhood Respiratory Diseases.

Nicole Prince Sofina Begum Kevin M Mendez Lourdes G Ramirez Yulu Chen Qingwen Chen Su H Chu Priyadarshini Kachroo Ofer Levy Joann Diray-Arce Paolo Palma Augusto A Litonjua Scott T Weiss Rachel S Kelly Jessica A Lasky-Su

Published in: bioRxiv : the preprint server for biology (2024)

These findings suggested protein profiles as early as age 1 year predicted development of respiratory-related diseases through age 6 and were associated with changes in pathways related to amino acid and energy metabolism. These may inform new strategies to identify vulnerable individuals based on immune protein profiling.

Keyphrases

amino acid
network analysis
protein protein
binding protein
small molecule
single cell
young adults