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Central nervous system prophylaxis in large B-cell lymphoma: A British Society for Haematology Good Practice Paper.

Matthew R WilsonKate CwynarskiToby Andrew EyreJeffery SmithSridhar ChagantiChristopher Paul FoxPamela McKay
Published in: British journal of haematology (2024)
This Good Practice Paper provides recommendations for the baseline investigation, risk stratification and use of prophylactic interventions for patients with large B-cell lymphoma at risk of central nervous system relapse. Recent evidence which has questioned the role of high-dose methotrexate in this clinical scenario is discussed in detail.
Keyphrases
  • high dose
  • diffuse large b cell lymphoma
  • primary care
  • healthcare
  • cerebrospinal fluid
  • low dose
  • stem cell transplantation
  • quality improvement
  • clinical practice
  • free survival