Central nervous system prophylaxis in large B-cell lymphoma: A British Society for Haematology Good Practice Paper.
Matthew R WilsonKate CwynarskiToby Andrew EyreJeffery SmithSridhar ChagantiChristopher Paul FoxPamela McKayPublished in: British journal of haematology (2024)
This Good Practice Paper provides recommendations for the baseline investigation, risk stratification and use of prophylactic interventions for patients with large B-cell lymphoma at risk of central nervous system relapse. Recent evidence which has questioned the role of high-dose methotrexate in this clinical scenario is discussed in detail.