In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR-/-ApoB100/100 mice.

Fabiana BlancoSuvi E HeinonenErika GurzelerLisa M BerglundAnna-Maria Dutius AnderssonOlga KotovaAnn-Cathrine Jönsson-RylanderSeppo Ylä-HerttualaMaria F Gomez

Published in: Diabetes & vascular disease research (2018)

Targeting the nuclear factor of activated T-cells signalling pathway may be an attractive approach for the treatment of diabetic macrovascular complications.

Keyphrases

nuclear factor
toll like receptor
type diabetes
coronary artery disease
risk factors
immune response
high fat diet induced
metabolic syndrome
pi k akt
signaling pathway
insulin resistance