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Investigating subtle kidney injury in primary hyperparathyroidism by means of sensitive and specific biomarkers.

Cristiana CiprianiJessica PepeLuciano ColangeloValeria FassinoMarco OcchiutoPiergianni BiondiLuciano NiedduSalvatore Minisola
Published in: Clinical endocrinology (2019)
We propose the utilization of these molecules, particularly urine KIM-1/uCr and urine NGAL/uCr ratios for the assessment of subtle kidney injury in patients with PHPT. These molecules are elevated in tubular necrosis and have potential role in the development of kidney damage in PHPT, according to the severity of the disease.
Keyphrases
  • oxidative stress