Abemaciclib: The First FDA-Approved CDK4/6 Inhibitor for the Adjuvant Treatment of HR+ HER2- Early Breast Cancer.

Farah RaheemHenry Ofori Lacey Simpson Vishal S Shah

Published in: The Annals of pharmacotherapy (2022)

Adjuvant abemaciclib significantly reduces the risk for early development of invasive disease and distant recurrence in patients with HR+, HER2- node positive EBC. Longer follow-up is needed to determine the impact of adjuvant abemaciclib on late disease recurrence and survival outcomes.

Keyphrases

early stage
early breast cancer
lymph node
combination therapy
drug administration
replacement therapy