Intra-individual changes in sperm DNA fragmentation levels over short and long time periods.

Gilad KaravaniMohamed S KattanSusan LauKirk C LoEthan D GroberBader AkroofKatherine LajkoszBrendan MullenKeith Jarvi

Published in: Journal of assisted reproduction and genetics (2023)

This study shows that DFI, in men being investigated for infertility, initially decreases in the first 3 years of follow-up, and then increases over time with the highest increase occurring after 5 years interval (an average increase of 10.8%). Testing infertile men's DFI levels at first evaluation may contribute to personalized consult regarding future reproductive outcomes.

Keyphrases

polycystic ovary syndrome
middle aged
circulating tumor
current status
type diabetes
skeletal muscle