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Biomimetic total syntheses of renifolin F and antiarone K.

Jarish AhamadFaiz Ahmed Khan
Published in: Organic & biomolecular chemistry (2024)
The first biomimetic and concise racemic total syntheses of renifolin F and antiarone K, accomplished in 8 and 7 linear steps, respectively, are presented in this article. Our synthetic approach commences with substituted aldehydes to produce prenylated aldol products followed by ene-type intramolecular cyclization affording a five-member core ring. This key step mediated by InCl 3 ·4H 2 O is a novel procedure first utilized in prenylated systems which directly culminates mainly into tertiary alcohols.
Keyphrases
  • tissue engineering
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  • minimally invasive
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  • quantum dots