Leg ulcers are indicators of systemic dysfunction in individuals with sickle cell disease.

Tiffany A JacksonAshley J BuscettaHasmin C RamirezVence L BonhamCaterina P Minniti

Published in: American journal of hematology (2024)

Leg ulcers in individuals living with Sickle Cell Disease are evidence of systemic dysfunction. Data from a U.S. study link leg ulcers to wider pulse pressure and markers of chronic hemolysis, inflammation, renal, and liver dysfunction.

Keyphrases

oxidative stress
blood pressure
wound healing
electronic health record
data analysis