Systematic review and exploratory meta-analysis of the efficacy, safety, and biological effects of psychostimulants and atomoxetine in patients with schizophrenia or schizoaffective disorder.

Marco SolmiMichele FornaroKuniyoshi ToyoshimaAndrè F CarvalhoCristiano A KöhlerNicola VeroneseBrendon StubbsAndrea de BartolomeisChristoph U Correll

Published in: CNS spectrums (2020)

No efficacy for stimulants or atomoxetine on negative symptoms is proven. Atomoxetine or amphetamines may improve cognitive symptoms, while methylphenidate should be avoided in patients with schizophrenia. Insufficient evidence is available to draw firm conclusions.

Keyphrases

systematic review
attention deficit hyperactivity disorder
meta analyses
autism spectrum disorder
sleep quality
depressive symptoms