mRNAs in skin surface lipids unveiled atopic dermatitis at one month.

Kiwako Yamamoto-HanadaMayako Saito-AbeKyoko Shima Satoko FukagawaYuya UeharaYui UedaMaeko IwamuraTakatoshi MuraseTetsuya KuwanoTakayoshi InoueYukihiro Ohya

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)

We identified molecular changes in barrier function and inflammatory markers that characterize the pathophysiology of AD in infants aged one month. We also revealed that neonatal acne at one month could predict the subsequent development of AD by sebum transcriptome data.

Keyphrases

atopic dermatitis
single cell
gene expression
rna seq
electronic health record
genome wide
big data
single molecule
artificial intelligence