Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.

Zhihui JingXinran FengXin LiXiaoyu ZhangChunling Pan

Published in: Journal of periodontal research (2024)

In summary, vaspin observably reduces HG-mediated inhibition of PDLSCs OD by modulating the TGF-β1/Smad signaling pathway. Vaspin may be a potential therapeutic for periodontal tissue regeneration in diabetic patients.

Keyphrases

signaling pathway
stem cells
epithelial mesenchymal transition
transforming growth factor
pi k akt
induced apoptosis
cell therapy
fluorescent probe
cell proliferation
mesenchymal stem cells
wound healing
endoplasmic reticulum stress