β-type TiNbSn Alloy Plates With Low Young Modulus Accelerates Osteosynthesis in Rabbit Tibiae.
Kentaro ItoYu MoriMasayuki KamimuraMasashi KoguchiHiroaki KurishimaTomoki KoyamaNaoko MoriNaoya MasahashiShuji HanadaEiji ItoiToshimi AizawaPublished in: Clinical orthopaedics and related research (2022)
An overly stiff plate may impair callus formation and bone healing. The TiNbSn alloy plate with a low Young modulus improves the early formation of new bone and stiff callus at the osteotomy site compared with the Ti6Al4V alloy plate in the healing process, which may promote bone repair. TiNbSn alloy may be a promising biomaterial for fracture treatment devices. Further research to address concerns about the strength of TiNbSn alloy plates, such as fatigue life and plate fracture, will be necessary for clinical applications, including mechanical tests to verify fatigue life and validation in larger animals with greater body weight.