Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome.

Chao WuYanqin BianBingjie LuDan WangNisma Lena Bahaji AzamiGang WeiFeng MaMing-Sun Yu

Published in: Journal of translational medicine (2022)

RFAs including rhein/diacerein, emodin, aloe emodin and 1,8-dihydroxyanthraquinone ameliorated NAFLD by inhibiting NLRP3 inflammasome. RFAs might be a potential therapeutic agent for NAFLD.

Keyphrases

nlrp inflammasome
signaling pathway
high fat diet induced
liver fibrosis
adipose tissue