Pediatric Ulcerative Colitis Is A Fibrotic Disease And Linked With Chronicity Of Inflammation.

Pediatric patients with ulcerative colitis exhibit colorectal submucosal fibrosis and muscularis mucosa thickening, which correlates with the presence, chronicity and degree of mucosal inflammation. Fibrosis should be recognized as a complication of pediatric ulcerative colitis, and ulcerative colitis should be considered a progressive disease.