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Clinical characteristics and prognosis of concomitant systemic lupus erythematosus and primary biliary cholangitis.

Cheng ChengZiqian WangLi WangJiuliang ZhaoQian WangXinping TianMeng Tao LiXiaofeng Zeng
Published in: Clinical rheumatology (2020)
Concomitant PBC might have a negative impact on the survival of SLE, with older age at SLE onset, longer delay before SLE diagnosis, and higher baseline damage. More intensive therapy and prevention of hepatic toxicity need to be considered. Key Points • Hematological and muscular involvement, PAH, and ILD were more common in SLE PBC than in SLE. • The study firstly reported the survival rate of SLE PBC patients. • More intensive therapy and prevention of hepatic toxicity are needed for SLE-PBC.
Keyphrases
  • systemic lupus erythematosus
  • disease activity
  • oxidative stress
  • rheumatoid arthritis
  • ejection fraction
  • newly diagnosed
  • physical activity
  • patient reported outcomes
  • patient reported