Clinical characteristics and prognosis of concomitant systemic lupus erythematosus and primary biliary cholangitis.
Cheng ChengZiqian WangLi WangJiuliang ZhaoQian WangXinping TianMeng Tao LiXiaofeng ZengPublished in: Clinical rheumatology (2020)
Concomitant PBC might have a negative impact on the survival of SLE, with older age at SLE onset, longer delay before SLE diagnosis, and higher baseline damage. More intensive therapy and prevention of hepatic toxicity need to be considered. Key Points • Hematological and muscular involvement, PAH, and ILD were more common in SLE PBC than in SLE. • The study firstly reported the survival rate of SLE PBC patients. • More intensive therapy and prevention of hepatic toxicity are needed for SLE-PBC.