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Seven-year outcome after 1-year fixed regimen of intravitreal aflibercept injections followed by pro re nata treatment for neovascular age-related macular degeneration.

Yuki HamaManabu MiyataSotaro OotoHiroshi TamuraNaoko Ueda-ArakawaYuki MuraokaMasahiro MiyakeAyako TakahashiTomotaka WakazonoAkihito UjiKenji YamashiroAkitaka Tsujikawa
Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2023)
BCVA was maintained for 7 years in nAMD eyes after 1-year fixed regimen of IVA, essentially followed by PRN regimen, but sometimes followed by agent switching, PDT, or vitrectomy, without severe drug-induced complications. Thus, early diagnosis and treatment of nAMD are essential for maintaining good long-term BCVA, even in eyes with relatively poor baseline vision.
Keyphrases
  • age related macular degeneration
  • drug induced
  • liver injury
  • optical coherence tomography
  • photodynamic therapy
  • risk factors
  • anti inflammatory
  • early onset
  • ultrasound guided
  • combination therapy