Takotsubo Syndrome: A Review of Presentation, Diagnosis and Management.
Joseph AssadGiuseppe FemiaPatrick PenderTamer BadieRohan RajaratnamPublished in: Clinical Medicine Insights. Cardiology (2022)
Takotsubo Syndrome (TTS) is a condition of transient left ventricular dysfunction that is typically triggered by emotional or physical stress. Since first described in Japan in 1990, it has increasingly been recognised in clinical practice, accounting for up to 2% of Acute Coronary Syndrome (ACS) presentations. In fact, the clinical presentation can be indistinguishable from a myocardial infarction. Although current evidence suggests a catecholamine induced myocardial stunning, the pathophysiological mechanisms remain unknown. Interestingly, it is more common in woman, particularly those who are post-menopausal. This review aims to summarise the current research and provide an overview of the diagnostic strategies and treatment options.
Keyphrases
- left ventricular
- acute coronary syndrome
- case report
- clinical practice
- heart failure
- percutaneous coronary intervention
- hypertrophic cardiomyopathy
- acute myocardial infarction
- cardiac resynchronization therapy
- physical activity
- antiplatelet therapy
- mitral valve
- oxidative stress
- mental health
- left atrial
- diabetic rats
- aortic stenosis
- stress induced
- coronary artery disease
- heat stress
- blood brain barrier