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Reference standards for gene fusion molecular assays on cytological samples: an international validation study.

Umberto MalapelleFrancesco PepePasquale PisapiaAnnalisa AltimariClaudio BellevicineHans BrunnströmRossella BrunoReinhard BüttnerLuis CirnesCarlos E De AndreaDario de BiaseCatherine I DumurKajsa Ericson LindquistGabriella FontaniniEugenio GautieroDavid GentienPaul HofmanVeronique HofmanAntonino IaccarinoMaria Dolores LozanoClara Mayo-de-Las-CasasSabine Merkelbach-BruseFabio PagniRuth RomanFernando C SchmittJanna SiemanowskiSinchita Roy-ChowdhuriGiovanni TalliniFrancesc TresserraSara Vander BorghtPhilippe VielhElena VigliarGiulia Anna Carmen VitaBirgit WeynandRafael RosellMiguel Angel Molina VilaGiancarlo Troncone
Published in: Journal of clinical pathology (2021)
Reference standards in cytological format yield better results when Pap staining and processed by amplicon-based assays. Further investigation is required to optimise these standards for MGG stained cells and for hybridisation-based approaches.
Keyphrases
  • induced apoptosis
  • high throughput
  • cell cycle arrest
  • genome wide
  • copy number
  • single molecule
  • genome wide identification
  • flow cytometry
  • single cell
  • pi k akt