Identification of lncRNA and mRNA Biomarkers in Osteoarthritic Degenerative Meniscus by Weighted Gene Coexpression Network and Competing Endogenous RNA Network Analysis.

Jun ZhaoYu SuJianfei JiaoZhengchun WangXiangchun FangXuefeng HeXiaofeng ZhangZhao LiuXilin Xu

Published in: BioMed research international (2020)

These hub lncRNAs and mRNAs were potential prognostic biomarkers for the meniscus degeneration of KOA. Further studies are required to validate these new biomarkers and better understand the pathological process of the meniscus degeneration of KOA.

Keyphrases

network analysis
anterior cruciate ligament
magnetic resonance imaging
risk assessment
copy number
gene expression
magnetic resonance
human health
transcription factor
case control
bioinformatics analysis
long noncoding rna
dna methylation
nucleic acid
climate change
contrast enhanced