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Silver carboxylate-TiO 2 /polydimethyl siloxane is a safe and effective antimicrobial with significant wound care potential.

Sai AlluColin WhitakerBenjamin StoneNeel VishwanathDrew ClippertElia JouffroyValentin AntociChristopher BornDioscaris R Garcia
Published in: OTA international : the open access journal of orthopaedic trauma (2024)
Current antimicrobial therapies in wound care and surgical antisepsis, such as chlorhexidine gluconate, have pitfalls including poor skin penetration and short duration of efficacy. The broad antimicrobial activity, extended elution, and deep skin penetration of this AgCar formulation show great promise for surgical site infection and wound care treatment. Novel technology to fight the growing threat of microbial resistance should be at the forefront of orthopaedic surgical site infection prevention and treatment.
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