BAFFR expression in circulating T follicular helper (CD4 + CXCR5 + PD-1 + ) and T peripheral helper (CD4 + CXCR5 - PD-1 + ) cells in systemic lupus erythematosus.
Nefertari Sagrero-FabelaPablo C Ortíz-LazarenoDiana C Salazar-CamarenaAlvaro CruzSergio Cerpa-CruzJosé F Muñoz-ValleMiguel Marín-RosalesJhonatan A Alvarez-GómezClaudia Azucena Palafox-SánchezPublished in: Lupus (2023)
This study emphasizes the importance of cTfh and Tph cells in SLE pathogenesis. Besides the importance of IL-21, our results suggest that BAFFR could play a role in cTfh and Tph subpopulations in the autoimmunity context.