Proteomic profiling of the plasma of Gambian children with cerebral malaria.
Ehab M MoussaHonglei HuangMarie L ThézénasRoman FischerAbhinay RamaprasadFatou Sisay-JoofMuminatou JallowArnab PainDominic KwiatkowskiBenedikt M KesslerCliment Casals-PascualPublished in: Malaria journal (2018)
The results indicate that increased tissue damage and hypercoagulability may play an important role in fatal CM. The diagnostic value of this molecular signature to identify children at high risk of dying to optimize patient referral practices should be validated prospectively.