N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling.

Xiaoli ShiYunzhu CenLiying ShanLijie TianEndong ZhuHairui YuanXiaoxia LiYing LiuBaoli Wang

Published in: Stem cell research & therapy (2022)

This study has provided evidences that NDRG1 plays a role in reciprocally modulating osteogenic and adipogenic commitment of marrow stromal progenitor cells through inactivating canonical Wnt signaling.

Keyphrases

bone marrow
signaling pathway
transcription factor
mesenchymal stem cells
stem cells
cell proliferation
copy number
dna methylation