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Small Molecule SHP2 Inhibitor LXQ-217 Affects Lung Cancer Cell Proliferation in Vitro and in Vivo.

Hao SunXiaoyi BaiYiting ZhangYanan GaoJiajia DaiPan XingJiqiang ZhuRuihua LiuZemin WangXiang-Qian Li
Published in: Chemistry & biodiversity (2024)
Our findings on the uncharged orthosteric inhibitor provide a foundation for further development of a safe and effective anti-lung cancer drug.
Keyphrases
  • small molecule
  • cell proliferation
  • cell cycle
  • protein protein
  • drug induced
  • signaling pathway
  • electronic health record